By James C. Bobrow MD

ISBN-10: 1615251189

ISBN-13: 9781615251186

Reports the anatomy, body structure, embryology and pathology of the lens. Covers the epidemiology, overview and administration of cataracts; provides an summary of lens and cataract surgical procedure; and explores the issues and unique occasions of cataract surgical procedure. final significant revision 2008 2009.

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Extra info for 2011-2012 Basic and Clinical Science Course, Section 11: Lens and Cataract (Basic & Clinical Science Course)

Example text

Potential complications of ectopia lentis include cataract and displacement of the lens into the anterior chamber or into the vitreous. Dislocation into the ante rior chamber or pupil may cause pupillary block and angle-closure glaucoma. Dislocation of the lens posteriorly into the vitreous cavity often has no adverse sequelae. Trauma is the most common cause of acquired lens displacement. Nontraumatic ectopia lentis is commonly associated with Marfan syndrome, homocystinuria, aniridia, and congenital glaucoma.

Near visual acuity tends to be reduced more than distance visual acuity. Some patients experience monocular diplopia. iF-lf - - - Vacuoles ----lib ---+-'< Nucleus (mild sclerosis) B Figure 5-5 A, Mature cortica l cataract. 8, Schematic of mature cort ical cataract. (Courtesy of ClBA Pharmaceutica l Co. , division of CIBA-GEIGY Corp. Reproduced with permission from Cli nical Symposia. Illustration by John A. ) Slit-lam p detection of PSCs can best be accomplished th rough a dilated pupil. Retro illumination is also helpful.

Marfan syndrome is believed to result from an abnormality of fibrillin, a connective tissue component. Affected individuals are tall, with arachnodactyly (Fig 4-15A) and chest wall deformities. Associated cardiac abnormalities include dilated aortic root and mitral valve prolapse. From 50% to 80% of patients with Marfan syndrome exhibit ectopia lentis (Fig 4-15B). The lens subluxation tends to be bilateral and symmetric (usually superior and temporal), but variations do occur. The zonular attachmen ts commonly remain intact but become stretched and elongated.

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